2. Neurological Disease

Neurological Disease

Neurological Disease

Related Products

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A range of neurological disorders, including epilepsy and dystonia, may involve dysfunctional intracortical inhibition, and may respond to treatments that modify it. Parkinson’s is a neurodegenerative disease characterized by increased activity of GABA in basal ganglia and the loss of dopamine in nigrostriatum, associated with rigidity, resting tremor, gait with accelerating steps, and fixed inexpressive face. Neurological deficits, along with neuromuscular involvement, are characteristic of mitochondrial disease, and these symptoms can have a dramatic impact on patient quality of life. Neurological features may be manifold, ranging from neural deafness, ataxia, peripheral neuropathy, migraine, seizures, stroke‐like episodes and dementia and depend on the part of the nervous system affected.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N0718R
    Valepotriate (Standard) 18296-44-1
    Valepotriate (Standard) is the analytical standard of Valepotriate. This product is intended for research and analytical applications. Valepotriate can be isolated from Valeriana jatamansi Jones, has anti-epileptic and anti-cancer activities.
    Valepotriate (Standard)
  • HY-N0730R
    Diosgenin glucoside (Standard) 14144-06-0
    Diosgenin glucoside (Standard) is the analytical standard of Diosgenin glucoside. This product is intended for research and analytical applications. Diosgenin glucoside, a saponin compound extracted from Trillium tschonoskii, provides neuroprotection by regulating microglial M1 polarization. Diosgenin glucoside protects against spinal cord injury by regulating autophagy and alleviating apoptosis .
    Diosgenin glucoside (Standard)
  • HY-N0748R
    Oxypaeoniflorin (Standard) 39011-91-1
    Oxypaeoniflorin (Standard) is the analytical standard of Oxypaeoniflorin. This product is intended for research and analytical applications. Oxypaeoniflorin, an anti-oxidant, is a monoterpene glycoside compound isolated from Paeoniae species. Oxypaeoniflorin has neuroprotective and anti-inflammatory effects.
    Oxypaeoniflorin (Standard)
  • HY-N0752R
    Scutellarein (Standard) 529-53-3
    Scutellarein (Standard) is the analytical standard of Scutellarein. This product is intended for research and analytical applications. Scutellarein is a natural flavonoid compound with anti-inflammatory effects.
    Scutellarein (Standard)
  • HY-N0765R
    Isoliquiritin (Standard) 5041-81-6
    Isoliquiritin (Standard) is the analytical standard of Isoliquiritin. This product is intended for research and analytical applications. Isoliquiritin, isolated from Licorice Root, inhibits angiogenesis and tube formation. Isoliquiritin also exhibits antidepressant-like, anti-oxidative, anti-Inflammatory effects and antifungal activity.
    Isoliquiritin (Standard)
  • HY-N0775R
    Isocorynoxeine (Standard) 51014-29-0
    Isocorynoxeine (Standard) is the analytical standard of Isocorynoxeine. This product is intended for research and analytical applications. Isocorynoxeine, an isorhynchophylline-related alkaloid, exhibits a dose-dependent inhibition of 5-HT2A receptor-mediated current response with an IC50 of 72.4 μM.
    Isocorynoxeine (Standard)
  • HY-N0783R
    Eupatilin (Standard) 22368-21-4
    Eupatilin (Standard) is the analytical standard of Eupatilin. This product is intended for research and analytical applications. Eupatilin, a lipophilic flavonoid isolated from Artemisia argyi Lévl. et Van., is a PPARα agonist, and possesses anti-apoptotic, anti-oxidative and anti-inflammatory activities.
    Eupatilin (Standard)
  • HY-N0784R
    Ginkgolide B (Standard) 15291-77-7
    Ginkgolide B (Standard) is the analytical standard of Ginkgolide B. This product is intended for research and analytical applications. Ginkgolide B (BN-52021), a terpene lactone, is a potent platelet activating factor antagonist. Ginkgolide B protects endothelial cells via the activation of PXR from injuries induced by xeno- and endobiotics. Ginkgolide B can pass through the brain-blood barrier. Ginkgolide B has anti-oxidant, anti-inflammatory, anti-tumor, and anti-apoptotic activity. Ginkgolide B has marked neuroprotective effects against ischemia-induced impairments.
    Ginkgolide B (Standard)
  • HY-N0786R
    Ginkgolide J (Standard) 107438-79-9
    Ginkgolide J (Standard) is the analytical standard of Ginkgolide J. This product is intended for research and analytical applications. Ginkgolide J is a main constituent of the non-flavone fraction of Ginkgo biloba with an IC50 range of 12-54 μM, has neuroprotective and anti neuronal apoptotic ability.
    Ginkgolide J (Standard)
  • HY-N0793A
    Protopine hydrochloride 6164-47-2 98%
    Protopine hydrochloride, an isoquinoline alkaloid, is a specific reversible and competitive inhibitor of acetylcholinesterase. Protopine hydrochloride exhibits anti-inflammation, anti-microbial, anti-angiogenic and anti-tumour activity.
    Protopine hydrochloride
  • HY-N0793R
    Protopine (Standard) 130-86-9
    Protopine (Standard) is the analytical standard of Protopine. This product is intended for research and analytical applications. Protopine (Corydinine), an isoquinoline alkaloid, is a specific reversible and competitive inhibitor of acetylcholinesterase. Protopine exhibits anti-inflammation, anti-microbial, anti-angiogenic and anti-tumour activity.
    Protopine (Standard)
  • HY-N0803S
    Myrcene-d6 75351-99-4 98%
    Myrcene-d6 is the deuterium labeled Myrcene. Myrcene (β-Myrcene) is a type of aromatic compound that inhibits TNFα and NF-κB activity. Myrcene has anti-invasive action, inhibits cell cycle, and leads to cancer cell apoptosis. Myrcene has strong blood protection effect, anti-inflammation, and anti-inflammatory activity.
    Myrcene-d6
  • HY-N0804A
    Isonaringin 108815-81-2 98%
    Isonaringin shows anti-Alzheimer’s activity by inhibiting AChE.
    Isonaringin
  • HY-N0809R
    Sesamolin (Standard) 526-07-8
    Sesamolin (Standard) is the analytical standard of Sesamolin. This product is intended for research and analytical applications. Sesamolin, isolated from Sesamum indicum, has antioxidative activity, Sesaminol inhibits lipid peroxidation and shows neuroprotection effect. Sesamolin potently inhibits MAPK cascades by preventing phosphorylation of JNK, p38 MAPKs, and caspase-3 but not ERK-MAPK expression.
    Sesamolin (Standard)
  • HY-N0810R
    Timosaponin AIII (Standard) 41059-79-4
    Timosaponin AIII (Standard) is the analytical standard of Timosaponin AIII. This product is intended for research and analytical applications. Timosaponin AIII could inhibit acetylcholinesterase (AChE) activity, with an IC50 of 35.4 μM.
    Timosaponin AIII (Standard)
  • HY-N0812R
    Timosaponin BII (Standard) 136656-07-0
    Timosaponin BII (Standard) is the analytical standard of Timosaponin BII. This product is intended for research and analytical applications. Timosaponin BII (Prototimosaponin A III) is a steroid saponin found in the rhizomes of Anemarrhena asphodeloides. Timosaponin BII has neuronal protective, anti-inflammatory and antioxidant activities.
    Timosaponin BII (Standard)
  • HY-N0820R
    Catalpol (Standard) 2415-24-9
    Catalpol (Standard) is the analytical standard of Catalpol. This product is intended for research and analytical applications. Catalpol (Catalpinoside), an iridoid glycoside found in Rehmannia glutinosa. Catalpol has neuroprotective, hypoglycemic, anti-inflammatory, anti-cancer, anti-spasmodic, anti-oxidant effects and anti-HBV effects.
    Catalpol (Standard)
  • HY-N0824R
    Syringin (Standard) 118-34-3
    Syringin (Standard) is the analytical standard of Syringin. This product is intended for research and analytical applications. Syringin (Eleutheroside B) is an active natural phenolic glycoside possessing various pharmacological activities, including anti-inflammatory, anti-irradiation, anti-osteoporosis and anticancer activities. Syringin also can be used to enhance memory, relieve fatigue, improve human cognition and protect ischemia heart against cerebrovascular damage, etc.
    Syringin (Standard)
  • HY-N0826R
    Corynoline (Standard) 18797-79-0
    Corynoline (Standard) is the analytical standard of Corynoline. This product is intended for research and analytical applications. Corynoline is a reversible and noncompetitive acetylcholinesterase (AChE) inhibitor with an IC50 of 30.6 μM. Corynoline exhibits anti-inflammatory activity by activating Nrf2.
    Corynoline (Standard)
  • HY-N0830A
    Palmitic acid calcium 542-42-7 98%
    Palmitic acid calcium is a long-chain saturated fatty acid commonly found in both animals and plants. PA can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells. Palmitic acid calcium is used to establish a cell steatosis model.
    Palmitic acid calcium
Cat. No. Product Name / Synonyms Application Reactivity